Chemical Biology & Radiation Therapy

Organic & Inorganic Chemical Synthesis

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The Organic Chemistry and Chemical Biology section is engaged in a variety of research activities that are underpinned by organic synthesis. Research activities cover a broad range of topics from the development of new reaction methodologies and catalysts, target asymmetric synthesis of molecules with profound biological activity, through to peptide, protein and DNA chemistry, radiochemistry and molecule imaging, single molecule detection, mass spectrometry, bionanotechnology, biocatalysis, chemical genetics and directed evolution.

The interface between inorganic chemistry and biology has been a rich one dating back several centuries. In more recent times, this field has been referred to as bioinorganic chemistry. The core of bioinorganic chemistry has focused on the study of metal sites in metalloproteins and metalloenzymes. Synthetic chemistry, an important component of chemical biology, has been used by bioinorganic chemists to make small molecule spectroscopy and functional models of metal sites in proteins. In addition, the use of small molecules to study biology also applies to inorganic complexes.